HCV carriers with normal aminotransferase levels: “normal” does not always mean “healthy”
نویسندگان
چکیده
منابع مشابه
HCV carriers with normal alanine aminotransferase levels: healthy persons or severely ill patients? Dealing with an everyday clinical problem.
Approximately 30% of patients with chronic HCV infection show persistently normal ALT levels. Although formerly referred to as 'healthy' or 'asymptomatic' HCV carriers, and thus historically excluded from antiviral treatment, it has now become clear that the majority of these patients have some degree of histological liver damage that may be significant in up to 20% of patients and might progre...
متن کاملHow to distinguish normal liver from chronic hepatitis in anti-HCV positive individuals with normal alanine aminotransferase levels.
The aim of this study was to characterize the biochemical, virological and histological profile of patients with HCV infection and persistently normal alanine aminotransferase levels (PNALT) in order to discriminate between normal liver and chronic hepatitis. Twenty eight anti-HCV positive patients with PNALT were studied. Twelve (42.9%) patients showed normal liver while 16 (57.1%) had chronic...
متن کاملDetection of hepatitis B activity in HBeAg-negative carriers with normal aminotransferase levels in central Brazil.
UNLABELLED BACKGROUND AND RATIONALE FOR THE STUDY: Hepatitis B virus (HBV) chronic infection may follow a benign course with low risk of cirrhosis or liver cancer. As differentiation of inactive status from HBeAg-negative chronic hepatitis B is often challenging, monitoring of inactive HBV carriers is important to detect viral relapse or formerly undetected activity. The incidence of hepatitis ...
متن کاملClinical Features of Hepatitis C Virus Carriers With Persistently Normal Alanine Aminotransferase Levels
Hepatitis C virus (HCV) infection causes chronic hepatitis, which frequently leads to hepatic fibrosis and hepatocellular carcinoma (HCC). Alanine aminotransferase (ALT) is a biomarker of hepatocyte injury and is associated with the progression of hepatic fibrosis. Advanced hepatic fibrosis also predisposes HCV carriers to a risk of HCC. In contrast, some cases with persistent HCV infection hav...
متن کاملclinical features of hepatitis c virus carriers with persistently normal alanine aminotransferase levels
hepatitis c virus (hcv) infection causes chronic hepatitis, which frequently leads to hepatic fibrosis and hepatocellular carcinoma (hcc). alanine aminotransferase (alt) is a biomarker of hepatocyte injury and is associated with the progression of hepatic fibrosis. advanced hepatic fibrosis also predisposes hcv carriers to a risk of hcc. in contrast, some cases with persistent hcv infection hav...
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ژورنال
عنوان ژورنال: Italian Journal of Medicine
سال: 2013
ISSN: 1877-9352,1877-9344
DOI: 10.4081/itjm.2009.88